The New England Patriots had some encouraging news on the injury front on Thursday with safety Kyle Dugger being upgraded as a limited participant after missing Wednesday’s practice.

However, the bad news was defensive tackle Christian Barmore being placed on the reserve non-football illness list due to recurring symptoms of his original blood clot diagnosis that kept him out for most of the season.

The injuries are piling up for the Patriots, and it isn’t just on the defensive side of the ball.

On offense, guard Cole Strange was a limited participant in practice with a knee injury, while rookie tackle Caedan Wallace was limited with an ankle injury. Meanwhile, veteran tackle Vederian Lowe has been nursing a shoulder injury.

Here’s the full injury list from Thursday’s practice:

Did not participate

DT Christian Barmore, Not Injury Related – Other

RB JaMycal Hasty, Ankle

CB Marcus Jones, Hip

Limited participation

S Kyle Dugger, Ankle / Illness

CB Christian Gonzalez, Shoulder

LB Anfernee Jennings, Knee

T Vederian Lowe, Shoulder

OL Cole Strange, Knee

LB Jahlani Tavai, Groin

OT Caedan Wallace, Ankle

DE Deatrich Wise Jr., Foot

It’ll be an uphill battle for the Patriots against quarterback Josh Allen and the Bills’ high-powered offense.

They’ll need all of the help they can get if they have any hope of toppling arguably the toughest opponent they’ve faced all season.